acetaminophen overdose napqi glutathione mechanism authoritative source Oxidative stress during hepatotoxicity: Sources, pathophysiological role and therapeutic potential When Good Drugs Go Bad:
Description
It defeats the purpose and may reduce effectiveness

Diarrhoea: Often resolves within approximately one week of onset

doi: 10.1371/journal.pone.0085387 [DOI] [PMC free article] [PubMed] [Google Scholar] 501
This allows for optimal absorption without interference from food