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Description
This NAD+ elevation activates sirtuins, particularly SIRT1 in adipocytes and hepatocytes, which deacetylates and activates numerous metabolic regulatory proteins including PGC-1, a master regulator of mitochondrial biogenesis, oxidative metabolism, and thermogenesis

Individuals with health conditions should consult their healthcare provider before starting B12 injections for safety

It is designated solely as a research chemical

Researchers continue investigating how NNMT-related mechanisms may affect obesity, glucose metabolism, and energy expenditure
