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Biochemical mechanisms of cisplatin cytotoxicity

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Surprisingly, the protein identified as having GULO-like activity is a sterol reductase, in contrast to GULO that is an aldonolactone oxireductase [20, 22]

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The Phase 3 SURMOUNT trials, which enrolled over 6,000 participants, did not exclude patients taking antioxidant supplements (including glutathione precursors like N-acetylcysteine)

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Z-scores are then aggregated at the gene-level into a normalised Z-score (normZ

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