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Am J Physiol-Regul, Integr Comp Physiol

2020;159:21632180.e6

Supplementary Data 1 (download XLSX The proteomics dataset and COG classification results shown in Fig

PCa cells and stromal components sustain a hypermetabolic state characterized by heightened dependence on glutamine and mTORC1-mediated suppression of autophagy, a process critical for oncogenesis, as evidenced by dysregulated autophagy-related genes (e.g., STK11/LKB1) upstream of mTORC signaling (198)
