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34 May 5-11, 2018 Westin La Paloma Resort, Tucson, AZ th Annual Society for Thermal Medicine Conference

On the right, the selenium-dependent glutathione peroxidase oxidizes two molecules of GSH back to GSSG in a reaction that converts one molecule of hydrogen peroxide (H 2 O 2 ) into two molecules of water (H 2 O)

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This interaction is mediated via endogenous cAMP, which at high level promotes opening, while at low level, induces blockage of HCN channels