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The use of L-dopa may be responsible for an increase in CSF total Homocysteine in PD patients (Isobe et al

ML162, which is selectively lethal to mutant RAS oncogene-expressing cells (with IC50s of 25 and 578 nM for HRAS G12V -expressing and wild-type RAS-expressing BJeHLT cells, respectively), is another GPX4 inhibitor to suppress tumor cell proliferation [197]

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