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The range ( 4.75.2) was removed to eliminate the effects of water peak suppression

Therefore, abnormal function of MTHFR leads to lower levels of folate derivatives and decreased DNA methylation

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When metabolic stress hits the cell (low energy, high oxidative load, glucose imbalance), MOTS-c is released from the mitochondria, enters the cytoplasm, and ultimately translocates into the cell nucleus where it regulates expression of stress-adaptation genes
