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One significant driver is the age-related decline in growth hormone (GH) secretion

Similarly, administration of epoxyeicosatrienoic acids (EETs) via the CYP2J2 pathway improves redox homeostasis in AEC2s, promotes Nrf2-dependent antioxidant responses, and indirectly stabilizes ER function by preserving phospholipid bilayer integrity (Zhang et al., 2023)
