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Thus, increased ROS production in T cells can occur as a result of metabolic reprogramming during T cell activation

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Overall, these data suggest that the Cu 3 -TC complexes are selective for the minor groove of duplex DNA and that heteroaromatic N,N donors provide enhanced DNA recognition properties

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[25] Murine cells overexpressing the NADase CD38 consumed less oxygen, had higher lactate levels, and had abnormal mitochondria, including traits like missing or enlarged cristae, which lends more proof of NAD+s role in promoting mitochondrial and metabolic health

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