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In the normal state of cells, Nrf2 binds to kelch-like ECH-associated protein-1 (Keap1) to form a complex, which exists in the cytoplasm

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The interplay between CBD, NO, and NOS suggests that CBD may serve as a vasodilatory agent, providing beneficial effects on vascular health, particularly in conditions characterized by endothelial dysfunction (Stanley et al

Many would develop scurvy, a life-threatening vitamin C deficiency