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These organ cross-talk mechanisms and the indirect effects of ALC via the improvement of liver and skeletal muscle metabolism, and thus the overall metabolism, might also explain the differences observed among trials and help the design of future studies by using objective measures of outcome and mechanisms of action of ALC

Tumova, E., Ebeid, T

Levocarnitine was not bound to plasma protein or albumin when tested at any concentration or with any species including the human.9 METABOLISM AND EXCRETION In a pharmacokinetic study where five normal adult male volunteers received an oral dose of [3H-methyl]-L-carnitine following 15 days of a high carnitine diet and additional carnitine supplement, 58 to 65% of the administered radioactive dose was recovered in the urine and feces in 5 to 11 days

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