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The protein kinase CK2 is involved in IR-induced cytokine production by endothelial cells, which ultimately leads to radiation resistance in non-small cell lung cancer cells [190]

Methods Enzymol 588:171186 Maruyama R, Shimizu M, Li J, Inoue J, Sato R (2016) Fibroblast growth factor 21 induction by activating transcription factor 4 is regulated through three amino acid response elements in its promoter region

however, these have not yet been translated into clinical practice ( In this review, we discuss briefly some of the principal mechanisms underlying the neurotoxicity induced by METH and summarize targeted pharmacologic treatments