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American Journal of Health-System Pharmacy , 81 , 385389
doi: 10.1016/S2213-2600(21)00127-2 44 AsciertoPAFuBWeiH
Inhibition of GCH1 reduced BH4 and resulted in enhanced erastin-induced iron accumulation and lipid peroxidation, thereby enhancing ferroptosis sensitivity, while BH4 supplementation suppressed ferroptosis-related changes caused by GCH1 downregulation
LeclercqSCaniPDNeyrinckAMStarkelPJamarFMikolajczakMet al
