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SS-31 prevented the cognitive deficits in aged mice and preserved hippocampal mitochondrial function

These effects show up over longer timelines as better overall vitality, slower functional decline, and stronger tissue repair

Complementary findings demonstrated that systemic immune activation via LPS in mice produced sustained reductions in novel object exploration for up to 24 h ( 3.2.4 Developmental and drug-induced microbiome disruption Disruptions to the gut microbiome during early development or the initial phases of psychiatric illness may influence the trajectory of mental disorders (Lavebratt et al., 2019) reported that early-life antibiotic exposure is linked to modestly increased risks for several childhood psychiatric disorders, including mood disorders, suggesting sensitive developmental windows for microbiome perturbations (Lavebratt et al., 2019)

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