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This makes it difficult to accurately predict in vivo behavior from laboratory data, necessitating more extensive animal and human trials (153)
Yet, these derivatives require electron ionization (EI) which lacks sensitivity
Comparably, cerebral amyloid angiopathy involves the buildup of amyloid within the arterial walls of small vessels, which also can weaken the vessel walls and cause rupture within the brain parenchyma [7]
Cummings DA
