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Intriguingly, when older mice were given MOTS-c injections to restore their MOTS-c to more youthful levels, it reversed certain aging effects specifically, it restored insulin sensitivity in aged muscles and improved the animals exercise capacity to levels comparable with younger mice

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The present study provides the first evidence that babies born to mothers with thrombophilia in the second trimester of intrauterine life experience intense oxidative stress characterized by overproduction of O2., NO, ONOO, and LPO, as well as GSH depletion