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In the current presentation, however, there was a marked progression in both the number and size of the pigmented lesions with a notable increase in pigmentation intensity

Interestingly, the strong dependence of mitochondrial -oxidation on autophagic and fatty acid (FA) catabolic processes makes some tumors more resistant to nutrient deprivation and environmental stressors 13

By identifying specific lipid species and lipid classes that are dysregulated in metabolic diseases, lipidomics studies have shed light on the molecular mechanisms underlying the development and progression of these disorders