glutathione reductase with nadph NADPH: Reductive Biosynthesis and Cellular Redox Control Full article: An in-silico approach
Description
Modeling interactions between leukemia-specific chromosomal changes, somatic mutations, and gene expression patterns during progression of core-binding factor leukemias
This alteration is strongly associated with IDH mutations and is almost mutually exclusive with ATRX mutations, reinforcing its role as a key molecular marker in glioma classification
This molecule has several actions but the most important is the inhibition of the uptake of the endogenous cannabinoid anandamide by neurons
It also stated that elevated glutathione levels raised antioxidant levels and resistance to oxidative stress in cancer cells
