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Continue Reading Injecting B12 into fat results in slower absorption, which may mean less B12 is wasted

Vitamin B12 and semen quality. Biomolecules 7.2 (2017): 42
Safety considerations: Common side effects of hydroxocobalamin include injection site pain, mild diarrhoea, itching, and rash Rarely, anaphylaxis may occur In severe deficiency, monitoring potassium levels may be necessary as rapid cell production can cause hypokalaemia Suspected adverse reactions should be reported via the MHRA Yellow Card Scheme If symptoms fail to improve or progress despite adequate treatment, alternative diagnoses should be reconsidered, and referral to neurology may be appropriate
It also must not be used for fluid replacement or volume expansion, and not for epidural or spinal anesthesia
