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In addition to fibrin activation, thrombin converts factor XIII to factor XIIIa, a highly specific transglutaminase that introduces cross-links composed of covalent bonds between the amide nitrogen of glutamines and -amino group of lysines in the fibrin monomers
It also supports the function and availability of anandamide, a naturally occurring neurotransmitter sometimes called the bliss molecule, which plays a role in mood, appetite, and calm behavior
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