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Neurosci Lett (2007) 422:249 10.1016/j.neulet.2007.05.025 [DOI] [PubMed] [Google Scholar] 87.Wollack JB, Makori B, Ahlawat S, Koneru R, Picinich SC, Smith A, et al

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The time course of drug in the body will depend on both the volume of distribution and the clearance: Because drug elimination can be described by an exponential process, the time taken for a twofold decrease can be shown to be proportional to the natural logarithm of 2

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