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Most diminutive is the Santa Cruz, flowing at a rate less than one-quarter that of the Salt

J Interferon Cytokine Res

To address this situation, researchers are exploring strategies such as using drugs that are less easily recognized by efflux pumps or co-administering efflux inhibitors to overcome MDR-mediated ADC resistance (see Section 6 for details)

Without them, free radicals are indeed "free" to cause oxidative stress
