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In:WirnitzerKetal., editors
The work shows that the molecule has the kind of properties selectivity, half-life, defined mechanism that a chemist would want as a starting point for medicinal optimization

After completing the injection, hold the needle in place for 5-10 seconds before withdrawing to prevent medication from leaking back along the needle track

Dose escalation is not always better starting low (300 mcg) and adjusting as needed is recommended