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Description
Thus, targeting MAM components represents a viable strategy to disrupt cancer cell metabolism and reduce resistance to apoptosis
It affects the ATP, one-carbon, redox and purine-metabolism environment that allows these pathways to move efficiently
Clinical trials of combined nivolumab and ipilimumab versus nivolumab or ipilimumab monotherapy in previously untreated melanoma have revealed that patients treated with nivolumab plus ipilimumab obtained durable and sustained clinical benefits
Mendoza et al
