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The adrenal glands also play a significant role in the bodys circadian rhythm through cortisol secretion
Furthermore, a deficiency of PGC-1 has been identified as a factor that inhibits the activity and function of dopaminergic neurons and causes behavioral dysfunction in the mouse central nervous system (Kuczynska et al., 2021)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Penefsky Z.J., Kahn M