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In conclusion, glutathione plays a critical role in the maintenance of brain health, and its depletion may contribute to the development and progression of MS

T cell transfer model (IL-23 driven): Transfer of naive CD4 + CD45RB hi T cells into immunodeficient mice results in IL-23-dependent colonic inflammation which mimics the T cell-driven immune response against intestinal antigens observed in human IBD ( 106 )

doi: 10.1038/sj.bjp.0707245 231 VriensJ.OwsianikG.HofmannT.PhilippS

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