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NQO1 C609T polymorphism is associated with coronary artery disease in a gender-dependent manner
De Groots Endocrinology
however, this enzyme may be retarded in Flavin insufficient states due to the fact that the second step in its pathway requires FAD for dimethyl glycine (DMG) HCY de-methylation and without sufficient FAD, DMG accumulates and the BHMT betaine degradation pathway is stalled (87)
