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Primary Prevention: Reducing Toxin Exposure Primary prevention of PD focuses on mitigating modifiable risk factors to delay or prevent disease onset [235, 236]
67 The PI3K/AKT pathway is a key signaling cascade linked to cell proliferation and is often dysregulated in cancer
Once again, the MDT provides substantial value at this stage, working interdisciplinarily to determine which metabolic axes exert the greatest influence on the clinical phenotype, whether these are linked to the genetic variants identified, and the most appropriate approach to address themwhether pharmacological, or through supplementation, nutrition, and lifestyle interventions
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