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Similarly, for FD (Lid/AG = 1/1), the solubility was approximately 223 mg/mL after 1 h and 215 mg/mL after 48 h, demonstrating an approximately 70-fold increase in solubility
The ability to predict the occurrence of seizures in subjects exposed to doses of CMI greater than 250 mg is limited, given that the plasma concentration of CMI may be dose-dependent and may vary among subjects given the same dose
