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Data Analysis and Consensus Definition After returning the answers of the first survey round, we calculated the mean and 80% confidence intervals (CIs) of the percentage of panelists who agreed with each of the answers

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The Akkermansia species muciniphila has been shown to alter glucose and lipid metabolism as well as intestinal immunity 86 , to strengthen the integrity of the enterocyte monolayer to possibly improve intestinal barrier integrity 87 , and to improve glucose tolerance and reduce visceral adipose tissue inflammation in mice fed an HFD 88

In Gram-negative bacterial infections, serum endotoxin measurements provide earlier detection of sepsis than the culture of bacterial pathogens themselves [55, 68]