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2001 May;24(5):875-80

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A separate 2024 meta-analysis (Alshammari et al.) confirmed the same conclusion, further strengthening the evidence base

As a pharmacist, a big eye-opening perspective on histamine intolerance for me was the role of psychiatric medications with histamine activity in people who have histamine-induced psychiatric issues. People are often aware that they receive antihistamine medications for their allergies, but may not be aware their reflux medications are also antihistamines (some work on histamine 2 receptors, H2 blockers)