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Consequently, AOXs have been utilized in the treatment of endometriosis, particularly for managing endometriosis-associated pain, with varying degrees of success (161163)

The Canadian journal of urology

IGF-1 has complex regulatory functions in adult human hematopoietic progenitor cells and can stimulate the proliferation of both myeloid and erythroid progenitors through its interactions with IGF-1 receptor (IGF-1R) 17,18

Because ER agonists can enhance cell proliferation in the adult hippocampus (Mazzucco et al., 2006), it therefore seems possible that TAM blockade of ER could suppress proliferation
