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Thus, targeting oxidative stress is crucial for treating LL-IRI

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doi: 10.1016/j.ekir.2021.04.023 93 AntarSAAshourNAMarawanMEAl-KarmalawyAA

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Addition of GGCT inhibition specifically targets the intrinsic mechanisms that enable glioblastoma cells to resist xCT inhibition, thereby providing a novel therapeutic strategy to efficiently induce ferroptosis in this highly aggressive and devastating malignancy

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