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In a microgravity environment, there are notable changes observed in intestinal epithelial cells and their tight intercellular connections, which contribute significantly to the increased permeability of the intestines

Structure-activity relationships of bumetanide derivatives: correlation between diuretic activity in dogs and inhibition of the human NKCC2A transporter

In addition, BaP induced DNA damage and activated the apoptotic pathway by upregulating expression of BAX and caspase-3 genes and downregulating BCL-2 genes