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However, under abnormal conditions (such as nutrient deprivation, oxidative stress, or exposure to cytotoxic agents), dysregulated autophagy can lead to cell death [7]
[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Immordino ML, Dosio F, Cattel L
-Alanine can be converted into MSA by two enzymes: 4-aminobutyrate-2-oxoglutarate transaminase (also called GABA-T or -alanine-2-oxoglutarate transaminase) and alanine-glyoxylate transaminase (also known as AGXT2 or -alanine-pyruvate transaminase) [44,45,46]
The second weakness is that the safety case is still structurally fragile
