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The discrepancy in effectors (AKT) phosphorylation and target genes (MyHC-S, MAFbx, and MuRF1) expression between EE/ICA and IGF-1 treatment may also hints for the application of different up-stream transducers by the two molecules

(2020), breast cancer cells with mutated BRCA1 exhibited enhanced resistance to platinum-based chemotherapy drugs due to the activation of alternative DNA repair mechanisms

Unlike their CD8+T cell counterparts, however, NK cells do not express the T cell receptor (TCR) on their surface and can be thought of as more of a pan-cellular innate surveillance cell

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