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Abbreviations MPS: Myofascial pain syndrome MTrPs: Myofascial trigger points SD: Sprague-dawley IGF-1: Insulin-like growth factor-1 IGF-1R: Insulin-like growth factor-1 receptor TBs: Taut bands WB: Western blotting HE: Hematoxylin-eosin staining IHC: Immunohistochemistry IOD: Integrated optical density PI3K: Phosphatidylinositol 3-kinase AKT: Protein kinase B mTOR: Mammalian target of rapamycin MLCK: Myosin light chain kinase EDTA: Ethylene-diaminetetraacetic acid PBS: Phosphate-buffered saline DAB: Diaminobenzidine PVDF: Polyvinylidene fluoride p-MLC: Phosphorylation of myosin light chain ACh: Acetylcholine TRPV2: Transient receptor potential vanilloid 2 TRP: Transient receptor potential References et al

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