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Fibroblastic Scaffolding: Visualizing the structural allocation of extracellular collagen networks laid by fibroblastic reticular cells (FRCs) that dictate lymphocyte migration trajectories

USA 92 , 15101514

Popova B, Wang D, Rajavel A, Dhamotharan K, Lazaro DF, Gerke J, Uhrig JF, Hoppert M, Outeiro TF, Braus GH

This copper peptide gene regulation manifests in several clinically significant ways: Downregulation of Pro-Inflammatory Genes: It actively suppresses genes associated with inflammation, such as those in the IL-6 and NF-B pathways, which are major drivers of cellular aging
