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Description
There was a positive trend in the Composite SLE Responder Index in the Intention-to-treat (ITT) cohort, and post-hoc analysis showed that the BILAG secondary endpoint was met for a number of subgroups dosing levels, including low or no steroids, seropositivity, and patients with 2 grade BILAG improvement

Enhance insulin sensitivity and reduce blood glucose levels, facilitating fat metabolism

Increase of CSF tyrosine and impaired serotonin turnover in tyrosinemia type I

& Weng, J