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Fibrosis: Sustained signaling drives fibroblast activation and extracellular matrix deposition Bone disorders: Impaired signaling alters bone remodeling and density, contributing to osteoporosis

Diagnosis often occurs incidentally, as fatty liver disease rarely causes symptoms in early stages
Phan CW, David P, Sabaratnam V (2017) Edible and medicinal mushrooms: emerging brain food for the mitigation of neurodegenerative disease

52 The hallmark features of COPD pathology are displayed in Figure 1