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In this study, the expression of Grx3 showed a positive correlation with that of survivin and cell survival rate

[DOI] [PubMed] [Google Scholar] 35.Podratz JL, Knight AM, Ta LE, et al
In this model, inflammation drives a massive upregulation of proangiogenic factors, which overwhelms the antiangiogenic mechanisms of the cornea and results in a secondary ingrowth of both blood and lymphatic vessels from the limbal area into the corneal center 15

This immune dysregulation is accompanied by a pro-inflammatory milieu, driven by cytokines, immune checkpoint molecules, and inflammatory mediators, which are increasingly recognized as potential diagnostic biomarkers
