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Annexin V binding with flow cytometric analysis showed no significant induction of early apoptosis at 6 h following R001 treatment, though evidence of extensive cell death of 56.2% occurred at later time (24 h), as indicated by Annexin V and FITC double positive staining (Fig
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Despite the promising results of a low-histamine diet for the treatment of dermatological conditions, scientific societies of dermatology still consider this exclusion diet of unproven utility pending randomized, double-blind, placebo-controlled clinical trials to confirm its effectiveness [121]
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