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Description
This metabolic perturbation significantly downregulates the expression of intestinal tight junction proteins, particularly ZO-1 (Mishra et al., 2023), thereby initiating a multistep pathogenic cascade: (i) compromised intestinal barrier integrity promotes bacterial translocation and systemic dissemination of deleterious metabolites
doi: 10.1210/jcem.79.4.7962295 119 SigalosJTPastuszakAW
Influence of -3 fatty acid eicosapentaenoic acid on IGF-1 and COX-2 gene expression in granulosa cells of PCOS women
What is ME/CFS
