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2016;152:R23R30

Compared to fibroblasts, myofibroblasts upregulate the expression of -SMA, and increase the production of extracellular matrix proteins, such as collagen type I, III, V and VI [256, 257]

Prevention of fistulas and stenosis Patients with IBD are often accompanied by intestinal fistula or intestinal cavity stenosis

Hit compounds identified from the high-throughput screen were validated via dose-response inhibition assays and further evaluated for cytotoxicity in MCF-7 estrogen and progesterone receptor-positive breast cancer cells and MDA-MB-231 triple-negative breast cancer cells
