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Lonafarnib and vemurafenib are FTIs approved to treat glioblastoma in the clinic (Figure 3)
Among these transporting processes, the receptor-mediated transporting process responsible for transferrin was the most investigated process and some of the brain targeting agents based on the process have been used effectively to develop brain targeting drug delivery systems
The major findings from these studies are summarized below
To date, numerous nanocarriers have been employed to increase drug penetration through the ocular barrier
