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Yang YA, Zhao JC, Fong KW, Kim J, Li S, Song C, et al
qRT-PCR Total RNA was extracted from tissues and cells using the TRIzol reagent (Invitrogen Life Technologies)

In a pivotal, multicenter, randomized phase III clinical trial involving 179 patients with DMD aged at least six years, givinostat effectively delayed disease progression

The resulting hexapeptide specifically and dose-dependently released GH both in vitro and in vivo through a mechanism entirely distinct from growth hormone-releasing hormone (GHRH)
