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Dillman et al, 2013), and thus, there might be an ongoing requirement for KAT6A for brain function, which might also benefit from treatment increasing histone acetylation levels

In the human condition Fanconi Anaemia, metabolic ROS were shown to induce DNA damage in hematopoietic stem cells (HSCs) when they start cycling to exit quiescence, which impairs blood production in FancA / mice 51

[DOI] [PubMed] [Google Scholar] 15.Ruan Y., Jiang S., Gericke A

Glutathione peroxidase (GPx) is found in all cells and uses GSH for detoxification of hydrogen peroxide and organic (lipid) peroxides in the cytosol and cell membranes (see Fig
