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This trans-port is ATP dependent

Washington, D.C.: ILSI Press

Yet, it has been shown that the import and folding of many cysteine-containing IMS proteins rely on the introduction of intramolecular disulfide bonds in the IMS, a process that is facilitated by the IMS-resident oxidoreductase Mia40 [66,171,172]

For patients on hemodialysis, consider doubling the acetylcysteine dose compared to what you would otherwise use (but dont increase it any higher than 25 mg/kg/hr)
