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DOI: 10.1002/jcb.240550004

The coregulator PGC-1 belongs to the PGC-1s family, whose members play a key role in the control of energy metabolism in many tissues and have been so far recognized as master regulators of mitochondrial biogenesis and antioxidant response 10,11,12,13

Compared with the modern environment, genetic factors on urate transporters have a larger effect on variation in serum urate concentrations (Major et al., 2018)

The importance of protecting the intestinal barrier before injury and restoration of barrier function after injury is crucial in various disease pathologies including celiac disease