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Description
Eliminating interference from IGFBPs can be achieved by removing them through effective yet laborious size exclusion chromatography at low pH but is more commonly achieved by acid-ethanol extraction and centrifugation
Its also the first-line treatment for acute and life-threatening neurological and cardiac complications of deficiency
The entire clinical development program, every pharmacokinetic study, every efficacy trial, every safety assessment, was conducted using subcutaneous injection
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